Towards a comprehensive view of the bacterial cell wall

Towards a comprehensive view of the bacterial cell wall Review

Journal

Trends in Microbiology
ISSN: 0966-842X , E-ISSN: 1878-4380

Output data

Year: 2005, Volume: 13, Number: 12, Pages: 569-574 Pages count : 6 DOI: 10.1016/j.tim.2005.10.001

Authors

Dmitriev Boris ¹ , Toukach Filip ² , Ehlers Stefan ³

Affiliations

1	N.F. Gamaleya Institute for Epidemiology and Microbiology, Gamaleya str. 18, Moscow 123098, Russia
2	N.D. Zelinsky Institute for Organic Chemistry, Leninsky Prosp. 33, Moscow 119991, Russia
3	Division of Molecular Infection Biology, Research Center Borstel, Parkallee 22, D-23845 Borstel, Germany

Direct in vivo visualization, in full atomic detail, of the microbial cell wall and its stress-bearing structural architecture remains one of the prime challenges in microbiology. In the meantime, molecular modeling can provide a framework for explaining and predicting mechanisms involved in morphogenesis, bacterial cell growth and cell division, during which the wall and its major structural component – murein – have to protect the cell from osmotic pressure and multiple tensile forces. Here, we illustrate why the scaffold concept of murein architecture provides a more comprehensive representation of bacterial cell wall physiology than previous models.

Dmitriev B. , Toukach F. , Ehlers S.
Towards a comprehensive view of the bacterial cell wall
Trends in Microbiology. 2005. V.13. N12. P.569-574. DOI: 10.1016/j.tim.2005.10.001 WOS Scopus OpenAlex

≡ Web of science:	WOS:000234014400005
≡ Scopus:	2-s2.0-27844566174
≡ OpenAlex:	W2166852006