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Glycoconjugate Vaccines for Prevention of Haemophilus influenzae Type b Diseases Обзор

Журнал Russian Journal of Bioorganic Chemistry
ISSN: 1608-330X , E-ISSN: 1573-9163
Вых. Данные Год: 2021, Том: 47, Номер: 1, Страницы: 26-52 Страниц : 27 DOI: 10.1134/s1068162021010106
Авторы Khatuntseva E.A. 1 , Nifantiev N.E. 1
Организации
1 Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia

Реферат: This review summarizes the experience in laboratory- and industrial-scale syntheses of glycoconjugate vaccines used for prevention of infectious diseases caused by Haemophilus influenzae type b bacteria based on the linear capsular polysaccharide poly-3-β-D-ribosyl-(1→1)-D-ribitol-5-phosphate (PRP) or related synthetic oligosaccharide ligands. The methods for preparation of related oligosaccharide derivatives and results of the studies evaluating effect of their length on immunogenic properties of the conjugates with protein carriers are overviewed.
Библиографическая ссылка: Khatuntseva E.A. , Nifantiev N.E.
Glycoconjugate Vaccines for Prevention of Haemophilus influenzae Type b Diseases
Russian Journal of Bioorganic Chemistry. 2021. V.47. N1. P.26-52. DOI: 10.1134/s1068162021010106 WOS Scopus OpenAlex
Идентификаторы БД:
≡ Web of science: WOS:000630869600002
≡ Scopus: 2-s2.0-85103353347
≡ OpenAlex: W3137454875
Альметрики: