Structural and serological studies of the O‐specific polysaccharide of the bacterium Proteus mirabilis O10 containing L‐altruronic acid, a new component of O‐antigens Научная публикация
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FEBS Letters
ISSN: 0014-5793 , E-ISSN: 1873-3468 |
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| Вых. Данные | Год: 1996, Том: 398, Номер: 2-3, Страницы: 297-302 Страниц : 6 DOI: 10.1016/s0014-5793(96)01061-7 | ||||
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Реферат:
An acidic O-specific polysaccharide from the lipopolysaccharide of Proteus mirabilis O10 contains 2-acetamido-2deoxy-d-glucose, 2-acetamido-2-deoxy-d-galactose, d-galacturonic acid, and l-altruronic acid, the last-named sugar having not been found hitherto in O-antigens. Structure of a branched tetrasaccharide repeating unit of the polysaccharide was established by 1H and 13C NMR spectroscopy, including two-dimensional COSY and rotating-frame NOE spectroscopy. The lateral l-altruronic acid residue plays the immunodominant role in manifestation of the O10 specificity of Proteus, whereas a disaccharide fragment of the main chain in common with the O-specific polysaccharide of P. mirabilis O43 provides the one-way serological cross-reactivity between anti-O10 serum and O43-antigen.
Библиографическая ссылка:
St. Swierzko A.
, Shashkov A.S.
, Senchenkova S.N.
, Toukach F.V.
, Ziolkowski A.
, Cedzynski M.
, Paramonov N.A.
, Kaca W.
, Knirel Y.A.
Structural and serological studies of the O‐specific polysaccharide of the bacterium Proteus mirabilis O10 containing L‐altruronic acid, a new component of O‐antigens
FEBS Letters. 1996. V.398. N2-3. P.297-302. DOI: 10.1016/s0014-5793(96)01061-7 Scopus OpenAlex
Structural and serological studies of the O‐specific polysaccharide of the bacterium Proteus mirabilis O10 containing L‐altruronic acid, a new component of O‐antigens
FEBS Letters. 1996. V.398. N2-3. P.297-302. DOI: 10.1016/s0014-5793(96)01061-7 Scopus OpenAlex
Идентификаторы БД:
| ≡ Scopus: | 2-s2.0-0030566813 |
| ≡ OpenAlex: | W1981847201 |