Fast highly efficient 'on-solvent' non catalytic cascade transformation of benzaldehydes and 4-hydroxycoumarin into bis(4-hydroxycoumarinyl)arylmethanes Научная публикация
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Arkivoc
ISSN: 1551-7012 , E-ISSN: 1551-7004 |
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| Вых. Данные | Год: 2017, Том: 2017, Номер: 3, Страницы: 121-129 Страниц : 9 DOI: 10.24820/ark.5550190.p010.023 | ||
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Реферат:
Non-catalytic cascade reaction of benzaldehydes and two equivalents of 4-hydroxycoumarin initiated by reflux in propanol results in the fast (15 min) and efficient formation of substituted tetrahydro-1H-xanthen-1-ones in 93–98% yields. The developed fast cascade approach to the substituted bis(4- hydroxycoumarinyl)arylmethanes, which are known as medicinally relevant substances with anti-HIV, antibiotic, anti-inflammatory and anti-cancer activity, is beneficial from the viewpoint of diversity-oriented large-scale processes and represents fast, efficient and environmentally benign synthetic concept for cascade reactions strategy.
Библиографическая ссылка:
Elinson M.
, Vereshchagin A.N.
, Sokolova O.O.
Fast highly efficient 'on-solvent' non catalytic cascade transformation of benzaldehydes and 4-hydroxycoumarin into bis(4-hydroxycoumarinyl)arylmethanes
Arkivoc. 2017. V.2017. N3. P.121-129. DOI: 10.24820/ark.5550190.p010.023 Scopus OpenAlex
Fast highly efficient 'on-solvent' non catalytic cascade transformation of benzaldehydes and 4-hydroxycoumarin into bis(4-hydroxycoumarinyl)arylmethanes
Arkivoc. 2017. V.2017. N3. P.121-129. DOI: 10.24820/ark.5550190.p010.023 Scopus OpenAlex
Идентификаторы БД:
| Scopus: | 2-s2.0-85103074120 |
| OpenAlex: | W2772778484 |