Synthesis of carbohydrate-amino acid conjugates related to the capsular antigen K54 from Escherichia coli O6:K54:H10 and artificial antigens therefrom Научная публикация
| Журнал |
Carbohydrate Research
ISSN: 1873-426X , E-ISSN: 0008-6215 |
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| Вых. Данные | Год: 1992, Том: 216, Страницы: 381-398 Страниц : 18 DOI: 10.1016/0008-6215(92)84175-r | ||
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Реферат:
The disaccharides α-l-Rhap-(1 → 3)-β-d-GlcpA and β-·-GlcpA-(1 → 3)-α-l-Rhap bearing amide- linked l-serine or l-threonine, which represent the repeating unit(s) of the capsular polysaccharide from E. coli O6:K54:H10, have been synthesised. O-tert-Butyl-protected amino acid tert-butyl esters were condensed with the corresponding biouronic acid as the 2-acrylamidoethyl or 2-azidoethyl glycosides. The azido function was replaced by the acrylamido group by catalytic hydrogenation followed by N-acryloylation. The tert-butyl groups were removed by treatment with trifluoroacetic acid to give the target monomers which were copolymerised woth acrylamide to give neococonjugates that are potentially useful for immunochemical studies.
Библиографическая ссылка:
Chernyak A.Y.
, Kononov L.O.
, Kochetkov N.K.
Synthesis of carbohydrate-amino acid conjugates related to the capsular antigen K54 from Escherichia coli O6:K54:H10 and artificial antigens therefrom
Carbohydrate Research. 1992. V.216. P.381-398. DOI: 10.1016/0008-6215(92)84175-r WOS Scopus OpenAlex
Synthesis of carbohydrate-amino acid conjugates related to the capsular antigen K54 from Escherichia coli O6:K54:H10 and artificial antigens therefrom
Carbohydrate Research. 1992. V.216. P.381-398. DOI: 10.1016/0008-6215(92)84175-r WOS Scopus OpenAlex
Идентификаторы БД:
| Web of science: | WOS:A1991GH58600032 |
| Scopus: | 2-s2.0-0026414077 |
| OpenAlex: | W2043481907 |