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1
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Vereshchagin A.
, Frolov N.A.
, Tyutin A.A.
, Tyurina A.N.
, Seferyan M.A.
, Detusheva E.V.
, Son E.
, Saverina E.A.
Expanding the Variety of Pyridinium‐Based bis‐QACs with Antimicrobial Properties: Investigation into Linker Structure‐Activity Correlation.
ChemMedChem. 2025.
e202400972
. DOI: 10.1002/cmdc.202400972
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2
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Frolov N.A.
, Seferyan M.A.
, Detusheva E.V.
, Saverina E.A.
, Son E.
, Akchurin R.N.
, Kartseva A.S.
, Firstova V.V.
, Vereshchagin A.N.
Exploring the Correlation of Linker Structure and Antimicrobial Activities of Pyridinium-Based Cationic Biocides: Aromatic versus Aliphatic Architectures
European Journal of Medicinal Chemistry. 2025.
V.292. 117673
. DOI: 10.1016/j.ejmech.2025.117673
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3
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Ilin E.A.
, Frolov N.A.
, Seferyan M.A.
, Valeev A.B.
, Vinokurov A.D.
, Detusheva E.V.
, Son E.
, Medvedev M.G.
, Vereshchagin A.N.
Tackling the challenge of ML-assisted antibacterial activity prediction: One step closer to controlled quaternary ammonium compounds design via neural networks model
Bioorganic Chemistry. 2025.
V.167. 109175
. DOI: 10.1016/j.bioorg.2025.109175
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4
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Frolov N.A.
, Seferyan M.A.
, Detusheva E.V.
, Son E.
, Kolmakov I.G.
, Vereshchagin A.N.
In Pursuit of a Better Biocide Composition: Synergistic and Additive Effects of QAC-Based Formulations Against Planktonic and Biofilm Cultures
International Journal of Molecular Sciences. 2025.
V.26. N24. 12098
. DOI: 10.3390/ijms262412098
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5
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Saverina E.A.
, Frolov N.A.
, Tyutin A.A.
, Lantsova E.A.
, Detusheva E.V.
, Son E.
, Vereshchagin A.N.
Synthesis and antibacterial activity of new bis-quaternary ammonium compounds based on 2,5-diformylfuran and pentaerythritol
Russian Chemical Bulletin. 2025.
V.74. N4. P.1099-1105. DOI: 10.1007/s11172-025-4603-9
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6
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Frolov N.A.
, Seferyan M.A.
, Detusheva E.V.
, Son E.
, Kolmakov I.G.
, Kartseva A.S.
, Firstova V.V.
, Vereshchagin A.N.
, Elinson M.N.
Development of Naphthalene-Derivative Bis-QACs as Potent Antimicrobials: Unraveling Structure–Activity Relationship and Microbiological Properties
Molecules. 2024.
V.29. N23. 5526
. DOI: 10.3390/molecules29235526
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7
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Frolov N.A.
, Vereshchagin A.N.
Piperidine Derivatives: Recent Advances in Synthesis and Pharmacological Applications
International Journal of Molecular Sciences. 2023.
V.24. N3. P.2937-2937. DOI: 10.3390/ijms24032937
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8
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Saverina E.A.
, Frolov N.A.
, Kamanina O.A.
, Arlyapov V.A.
, Vereshchagin A.N.
, Ananikov V.P.
From Antibacterial to Antibiofilm Targeting: An Emerging Paradigm Shift in the Development of Quaternary Ammonium Compounds (QACs)
ACS Infectious Diseases. 2023.
V.9. N3. P.394-422. DOI: 10.1021/acsinfecdis.2c00469
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9
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Seferyan M.A.
, Saverina E.A.
, Frolov N.A.
, Detusheva E.V.
, Kamanina O.A.
, Arlyapov V.A.
, Ostashevskaya I.I.
, Ananikov V.P.
, Vereshchagin A.N.
Multicationic Quaternary Ammonium Compounds: A Framework for Combating Bacterial Resistance
ACS Infectious Diseases. 2023.
V.9. N6. P.1206-1220. DOI: 10.1021/acsinfecdis.2c00546
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10
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Frolov N.A.
, Seferyan M.A.
, Valeev A.B.
, Saverina E.A.
, Detusheva E.V.
, Vereshchagin A.N.
The Antimicrobial and Antibiofilm Potential of New Water-Soluble Tris-Quaternary Ammonium Compounds
International Journal of Molecular Sciences. 2023.
V.24. N13. 10512
. DOI: 10.3390/ijms241310512
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11
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Frolov N.A.
, Smirnov V.A.
, Detusheva E.V.
, Vereshchagin A.N.
Novel naphthalene-based bis-pyridinium compounds with pronounced antibacterial activity
Mendeleev Communications. 2022.
V.32. N5. P.606-608. DOI: 10.1016/j.mencom.2022.09.012
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12
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Frolov N.
, Detusheva E.
, Fursova N.
, Ostashevskaya I.
, Vereshchagin A.
Microbiological Evaluation of Novel Bis-Quaternary Ammonium Compounds: Clinical Strains, Biofilms, and Resistance Study
Pharmaceuticals. 2022.
V.15. N5. 514
. DOI: 10.3390/ph15050514
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13
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Vereshchagin A.N.
, Frolov N.A.
, Minaeva A.P.
, Detusheva E.V.
, Derkach Y.V.
, Egorov M.P.
Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives
Mendeleev Communications. 2021.
V.31. N3. P.368-369. DOI: 10.1016/j.mencom.2021.04.028
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14
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Vereshchagin A.N.
, Frolov N.A.
, Egorova K.S.
, Seitkalieva M.M.
, Ananikov V.P.
Quaternary Ammonium Compounds (QACs) and Ionic Liquids (ILs) as Biocides: From Simple Antiseptics to Tunable Antimicrobials
International Journal of Molecular Sciences. 2021.
V.22. N13. 6793
. DOI: 10.3390/ijms22136793
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15
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Vereshchagin A.N.
, Frolov N.A.
, Konyuhova V.Y.
, Kapelistaya E.A.
, Hansford K.A.
, Egorov M.P.
Investigations into the structure–activity relationship in gemini QACs based on biphenyl and oxydiphenyl linker
RSC Advances. 2021.
V.11. N6. P.3429-3438. DOI: 10.1039/d0ra08900a
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16
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Vereshchagin A.N.
, Frolov N.A.
, Minaeva A.P.
, Detusheva E.V.
, Derkach Y.V.
, Egorov M.P.
Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives
Mendeleev Communications. 2021.
V.31. N3. P.368-369. DOI: 10.1016/j.mencom.2021.05.028
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17
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Frolov N.A.
, Fedoseeva K.A.
, Hansford K.A.
, Vereshchagin A.N.
Novel Phenyl‐Based Bis‐quaternary Ammonium Compounds as Broad‐Spectrum Biocides
ChemMedChem. 2021.
V.16. N19. P.2954-2959. DOI: 10.1002/cmdc.202100284
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18
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Vereshchagin A.N.
, Frolov N.A.
, Konyuhova V.Y.
, Dorofeeva E.O.
, Hansford K.A.
, Egorov M.P.
Synthesis and biological evaluation of novel bis-quaternary ammonium compounds with p-terphenyl spacer
Mendeleev Communications. 2020.
V.30. N4. P.424-426. DOI: 10.1016/j.mencom.2020.07.006
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19
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Vereshchagin A.N.
, Frolov N.A.
, Pakina A.S.
, Hansford K.A.
, Egorov M.P.
Synthesis and biological evaluation of novel bispyridinium salts containing naphthalene-2,7-diylbis(oxy) spacer
Mendeleev Communications. 2020.
V.30. N6. P.703-705. DOI: 10.1016/j.mencom.2020.11.004
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20
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Vereshchagin A.N.
, Frolov N.A.
, Konyuhova V.Y.
, Hansford K.A.
, Egorov M.P.
Synthesis and microbiological properties of novel bis-quaternary ammonium compounds based on 4,4′-oxydiphenol spacer
Mendeleev Communications. 2019.
V.29. N5. P.523-525. DOI: 10.1016/j.mencom.2019.09.015
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